Sunday, December 22
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Biotechnology

The Future of Pharmaceuticals

Biotechnology, Pharmaceutical Research and Development
The inter linking of medicine and technology is paving way for newer opportunities in pharmaceutical medication, surgery, and health monitoring. Medicine is increasingly being interspersed with fields such as computer science, nanotechnology and biotechnology to give hybrid fields that are slowly taking over traditional pharmaceuticals. Some of these fields are set to redefine the future of pharmaceuticals. Precision Medicine Precision medicine is a field that attempts at discovering the biological basis of disease using clinical and molecular information of a patient, obtained by converting DNA into data through genome sequencing. This data is used for identifying specific gene abnormalities that help understand which types of patients a drug would be most effective on, an...

Gene Therapy For Disease-Free Society

Biotechnology, Cure & Prevention, Medicine
As per several genome research organizations, a sizeable percentage of diseases acquired by newborns are genetic, which means the diseases were acquired through hereditary or mutations. In simpler terms, when the egg and the sperm (genetic material) fuse, the embryo formed will acquire some hereditary traits that may carry diseases. A random mutation, although rare, may cause an extremely rare genetic condition. Rather than making futile attempts at discovering newer drugs for genetic disorders, in May 1989, scientists made the first successful attempt at modifying human DNA by injecting favourable genes into the nucleus of the cell. This method, called gene therapy, ever since has been advancing by leaps and bounds. Coupled with the latest genetic editing tool called CRISPR/C...
Biomedical Intervention for Autism

Biomedical Intervention for Autism

Biotechnology
The use of biomedical therapies for people with any autism-spectrum condition is a process that involves patience as well as investigation. The patience aspect is very critical because different types of therapies work at different rates, while the investigation part of the equation is finding out which therapy is more effective than an alternate one. Learning how to track the progress in patients both physically and cognitively is essential. For example, with some patients, a Methyl-B 12 protocol for therapy can begin to work quickly and results can be seen in as little as one month. The results that have been seen are varied and include: Better speech More eye contact Longer attention span On the other hand, treatments like Hyperbaric Oxygen Therapies are recommended by ...
Personalised Cell Therapy

Personalised Cell Therapy

BioPharma, Biotechnology, Pharmaceutical Quality Assurance, Pharmaceutical Research and Development
Personalised treatment Personalised medical treatment has matured to integrate into biopharmaceutical drug development pathways. This type of treatment targets patient/s with a specific drug that matches the specific disease physiopathology and/or patient characteristics e.g. genomic profile, and disease prevalence/severity. Personalised medicine has been generally developed in niche indications or conditions with high unmet need. Cell therapy, transplantation and the HLA matching Cell therapy uses cellular entities as prophylactic or therapeutic drugs/treatments. An ancestor of today’s cell therapy is transplanting hematopoietic stem cells to reset immune systems after intensive leukaemia chemotherapy. Treatment personalisation is essential to match the graft to the recipient(HLA match...
Clinical Trials on tissues of human heart now possible in UK

Clinical Trials on tissues of human heart now possible in UK

Biotechnology, Clinical Trials, Drug Development, Pharmaceutical Research and Development
A UK based new start-up is developing a unique method for testing out the impact of drugs on the cardio-vascular system without resorting to animal testing or through clinical trials of an early-stage human. The company we are talking about is Inocardia, a spin-out from the University of Coventry. Having attracted sufficient funding from the Mercia Fund Management, this organization is still in the process of shaping up the model and commercializing their line of business. The model that they use takes up samples of the human heart attached to a rig. The cardiac tissue is elongated and contracted through electric impulse stimulation so as to mimic a working human heart.Drugs to be trialed are then administered to the tissue to keep a track of adverse effects – a test that could have been...
Low-Cost Genome Sequencing

Low-Cost Genome Sequencing

BioPharma, Biotechnology, Cheminformatics, Drug Development, Drug Discovery, Economic and Regional Development, Pharma Industry
In Silicon Valley, Moore's law appears to remained on equivalent balance with the regular laws classified by Isaac Newton. Intel prime supporter Gordon Moore's notorious perception that registering power has a tendency to twofold — and that its value hence parts — like clockwork has held valid for about 50 years with just minor update. Yet as a model of quick transform, it is the focus of energetic ill-use from genome analysts. In many presentations over the past few years, researchers have contrasted the slant of Moore's law and the quickly dropping expenses of DNA sequencing. For some time they kept pace, however since something like 2007, it has not even been close. The cost of sequencing a normal human genome has plunged from about Us$10 million to a couple of thousand dollars in only...
Future of Pharma Industry – Biotechnology

Future of Pharma Industry – Biotechnology

BioPharma, Biotechnology, Pharma Industry, Pharmaceutical Business Development
Biotechnology can be defined as the use of living systems and organisms to develop or make useful products, or "any technological application that uses biological systems, living organisms or derivatives in order to make or modify products or processes for specific use.  However, contrary to its name biotechnology is not a single technology. Rather it is a group of technologies that share two (common) characteristics; working with living cells and their molecules and having a wide range of practice uses that can improve our lives. Traditional biotechnology has been practiced since the beginning of records history.  It has been used to enhance the agricultural production, to bake bread, brew alcoholic beverages, and breed food crops or domestic animals. Through early biotechnology, the ear...