Personalised Cell Therapy
Personalised treatment
Personalised medical treatment has matured to integrate into biopharmaceutical drug development pathways. This type of treatment targets patient/s with a specific drug that matches the specific disease physiopathology and/or patient characteristics e.g. genomic profile, and disease prevalence/severity. Personalised medicine has been generally developed in niche indications or conditions with high unmet need.
Cell therapy, transplantation and the HLA matching
Cell therapy uses cellular entities as prophylactic or therapeutic drugs/treatments. An ancestor of today’s cell therapy is transplanting hematopoietic stem cells to reset immune systems after intensive leukaemia chemotherapy. Treatment personalisation is essential to match the graft to the recipient(HLA match...